At the Research level
The cure for
many ocular surface diseases will only be possible once corneal sensitivity,
and lachrymal functions governing corneal health can be re-established or when those
mechanisms are fully understood and eventually artificially reproduced.
Hence, we have written this chapter to address research leads aiming at re-establishing a normal corneal metabolism or destined to improve
healing or certains components of tears.
Another aspect would controlling and modulating
pain signals, because currently reducing pain artificially may further
compromise unheatlhy eye surface. Let's remeber that pain sign are involved in
healing and tearing and without them we would tend to recreate neurotrophic dry
eye (one of the worts forms of dry eye).
To sum up, our main areas of interest
corneal healing and transparency
improving tears and its components
or its replacements
innovative treatments enabling to
protect the eye surface, reduce pain and visual sequels in many OSD (see
our section on
re-establishing sensitivity in
for the worst cases of OSD,
keratoprothesis and scleral lenses.
growth factors or neuropeptides and
biomedical treatments containing growth factors.
Studies enabling a better
understanding of the mechanisms implicated in the normal surface
metabolism so as to be able to reproduce it.
Keratos desires to raise awareness
among the general population regarding the challenges that these
diseases face in social, familiar or professional life. It's surely the
ony way to improve medical and social care for, and to change behavior
towards, OSD sufferers.
In sum, are main social interests are:
better awareness regarding the
pathologies and their impact.
improve awareness on our professional
make society to adopt better
behaviour towards OSD sufferers (no tabacco,
limited air-conditioner, limeted heating).
improve medical care,
increase research on ocular surface
force administration to recognise
ocular pain as debilitating.
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